Professional Experience

Associate Director, Exploratory Research (03/2024 - Present)

• Project team lead for research projects from PoC through lead selection and onto DC nomination. Close collaboration with senior research and development team stakeholders to define TPP and perform stage-appropriate derisking as research projects progressed through Mythic's pipeline.
• Research pipeline management from exploratory stage onto PoC and DC nomination. Led cross-functional stage-gate meetings, guided the team on identifying and mitigating biological (target-related) and platform (linker-toxin) risks and lead selection.
• Scientific leader who cultivated a broad understanding of the therapeutic landscape and opportunities through key opinion leader (KOL) outreach, scientific conference attendance, and literature review. Engaged with internal and external stakeholders including scientific advisory board and board of directors to align research priorities.

Sr. Scientist, Biologics (02/2021 - 03/2024)

• Engineered and evaluated bispecific antibodies to advance internal oncology programs. Managed internal and external partners on the production, QC, and testing of these molecules as naked mAbs and ADCs in in vitro (HPLC, BLI, ELISA, Cytotox) and in vivo (CDX, PDX, PK) and in silico (immunogenicity) assays.
• Effectively communicated with internal and external stakeholders as a protein engineering technical lead and project lead in a matrixed environment. Managed vendors responsible for critical reagent generation.
• Built an internal antibody characterization pipeline to assess therapeutic antibody developability along with biological activity. Analyzed and compiled data from multiple sources to determine lead molecules in programs that had hundreds of candidates and thousands of variants.

Scientist, Biologics (09/2018 - 07/2021)

• As a part of a small scientific team, laid the groundwork for Mythic's FateControl technology. Innovated creative solutions to meet the aggressive deadlines of a seed-stage biotech, culminating in DC nomination of Mythic's clinical asset, MYTX-011.
• Designed and oversaw display-based and in vivo antibody discovery campaigns. Managed CROs running discovery campaigns and adapted the output to fit into Mythic's pipeline.
• Trained, mentored, and supervised junior scientists on relevant technical skills and techniques as well as core competencies to build more rounded and engaged team members.